BIOENERGY ASPECTS IN THE TREATMENT OF ACNE

V. V. Bocharova

Abstract


Subject of the study is the bioenergetic processes of microbiota of skin activity in patients with acne. Purpose of the work is to analyze influence microbiota of skin energetic metabolism mechanisms on formation of their associations and pathogenesis of the acne. Patients with acne have shown changes in the ratio of normal and conditionally pathogenic microflora of skin, which may depend on differences in the energy metabolism of different types of microorganisms. Consideration of bioenergetic aspects of microbial associations formation and activity at acne is necessary for adequate treatment of patients.

Keywords: acne, microbiota, Sanguirhytryn.

В. В. Бочарова, кандидат медицинских наук. Биоэнергетические аспекты лечения акне / Одесский национальный медицинский университет, Украина, Одесса

Предмет исследования – биоэнергетические процессы жизнедеятельности микробиоты у больных угревой болезнью. Цель работы – анализ влияния механизмов энергетического метаболизма микробиоты на формирование их ассоциаций и патогенез акне. У больных угревой болезнью выявлены изменения соотношения нормальной и условно патогенной микрофлоры кожи, которые могут зависеть и от отличий энергетического метаболизма разных видов микроорганизмов. Учет биоэнергетических аспектов формирования и жизнедеятельности микробных ассоциаций при акне необходим для проведения адекватной терапии больным.

Ключевые слова: угревая болезнь, микробиота, сангвиритрин.


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References


Simpson R. C. What’s new in acne? An analysis of systematic reviews and clinically significant trials published in 2010-2011 / R. C. Simpson, D. J. Grindlay, H. C. Williams // Clin. Exp. Dermatol. – 2011. – Vol. 36 (8). – P. 840-843.

Georgia F. The use of oral antibiotics in treating acne vulgaris: a new approach / F. Georgia, T. Ernest // Dermatologic Therapy. – 2016. – Vol. 29, N. 5. – P. 377-384.

Zouboulis C. C. Neuroendocrine regulation of sebocytes – a pathogenetic linkbetween stress and acne / C. C. Zouboulis // Exp. Dermatol. – 2004. – Vol. 13 (Suppl. 4). – P. 31-35.

Menha A. I. Evaluation of biomarkers of oxidant–antioxidant balance in patients with acne vulgaris / A. I. Menha, E. H. Manal, H. S. Hanan [et al.] // Journal of the Egyptian Women's Dermatologic Society. – 2015. – Vol. 12, N. 2. – P. 136-141.

Webster C. F. Inflammatory acne / C. F. Webster // Int. J. Dermatol. – 1990. – Vol. 29. – P. 313-317.

Pei-Feng L. Propionibacterium acnes in the Pathogenesis and Immunotherapy of Acne Vulgaris / L. Pei-Feng, H. Yao-Dung, L. Ya-Ching [et al.] // Current Drug Metabolism. – 2015. – Vol. 16, N. 4. – P. 245-254.

Jahns A. C. An increased incidence of Propionbacterium acnes biofilms in acne vulgaris: a case-control study / A. C. Jahns, B. Lundskog, R. Ganceviciene [et al.] // Br. J. Dermatol. – 2012. – Vol. 167. – P. 50-58.

Поздеев О. К. Медицинская микробиология / ред. В. И. Покровского. – М.: ГЭОТАР-Медиа. – 2008. – 768 с.

References:

Simpson R. C., Grindlay D. J., Williams H. C. (2011). What’s new in acne? An analysis of systematic reviews and clinically significant trials published in 2010-2011. Clin. Exp. Dermatol., 36(8), 840-843. [in English].

Georgia F., Ernest T. (2016). The use of oral antibiotics in treating acne vulgaris: a new approach. Dermatologic Therapy, 29(5), 377-384. [in English].

Zouboulis C. C. (2004). Neuroendocrine regulation of sebocytes – a pathogenetic linkbetween stress and acne. Exp. Dermatol., 13(4), 31-35. [in English].

Menha A. I., Manal E. N., Hanan H. S., et al. (2015). Evaluation of biomarkers of oxidant–antioxidant balance in patients with acne vulgaris. Journal of the Egyptian Women's Dermatologic Society, 12(2), 136-141. [in English].

Webster C. F. (1990). Inflammatory acne. Int. J. Dermatol., 29, 313-317. [in English].

Pei-Feng L., Yao-Dung H., Ya-Ching L., et al. (2015). Propionibacterium acnes in the Pathogenesis and Immunotherapy of Acne Vulgaris. Current Drug Metabolism, 16(4), 245-254. [in English].

Jahns A. C., Lundskog B., Ganceviciene R., et al. (2012). An increased incidence of Propionbacterium acnes biofilms in acne vulgaris: a case-control study. Br. J. Dermatol., 167, 50-58. [in English].

Pozdeev O. K. (2008) Medicinskaya mikrobiologiya; red. V. I. Pokrovskogo. Moscow: GEHOTAR-Media. [in Russian].




DOI: https://doi.org/10.26886/2523-6938.1(2)2018.2

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